莫秀梅
发布人: 星禧   发布时间: 2018-07-01    浏览次数:

莫秀梅

2010-09-02

学位:博士

职称:教授

所属部门:院外导师

导师身份:博士生导师

课题组:



职位:

教授


社会兼职:

为新加坡材料协会会员,中国生物医学工程学会生物材料分会理事,“Frontiers of Materials Science”杂志编委


研究方向:

纳米纤维,生物材料,组织工程


荣誉获奖:

上海市技术发明一等奖,国家科技进步二等奖


个人简历:

学习及工作简历: 1. 1978-1982年华东理工大学材料科学学院,高分子材料专业本科,获学士学位。 2. 1982-1985年华东理工大学材料科学学院,功能高分子方向硕士研究生,获硕士学位。 3. 1985-1988 青岛化工学院,高分子材料系,主讲高分子物理,高分子化学及工艺课,于1986年获讲师职称。 4. 1988-1991年中国纺织大学(现东华大学)材料学博士学位 5. 1991-1997华东理工大学材料科学学院,从事教学及科研工作。于19959月获副教授职称。 6. 1995.9-11 日本工业技术厅大阪工业技术研究院,客座研究员。 7. 1996.9-11日本工业技术厅大阪工业技术研究院,访问教授。 8. 1997-1999 日本京都大学,再生医科学研究所,参入日本JSPS资助的组织工程重大研究项目,从师于日本著名生物材料专家筏义仁教授,获博士后。完成了新型医用胶黏合剂的制备及医用性能的动物实验检验。 9. 1999-2003 新加坡国立大学研究员,参入了生物医学工程系的组建,协助建立了生物材料及纳米生物研究室。全面开展了生物材料用于与组织工程,骨组织,肌键和血管的再生的研究。 10. 2003-2004 德国亚琛工业应用技术大学访问教授,参入了DAAD资助的人造器官项目的科学研究,和国际硕士研究生的教学工作。 11. 20052月-3月:受德国亚琛工业技术大学的邀请,为国际硕士研究生开设生物材料和生物相容性的英语授课。 12. 200923月:Visiting Distinguished Researcher   Awards(卓著的访问学者) 13. 2004.11 迄今:东华大学生物科学与技术研究所教授,同时兼职于纤维改性国家重点实验室工作。已建成生物材料研究室和组织工程研究室各一个,启动了纳米生物医用材料仿生和组织再生的研究方向。为本科及硕士生开设了生物材料与生物相容性的中英文双语教学。主持和参入包括上海市科委重大、国家自然科学基金、科技部863项目、国家外专局聘专项目等十多项科研课题资助,指导硕博研究生科研20多名,发表论文200多篇,获得上海市技术发明一等奖和国家科技进步二等奖各1项。


主讲课程:

生物材料


已取得的主要研究成果:

纳米纤维组织工程血管、神经导管、皮肤


主要论文:

1. Anlin Yin, Kuihua Zhang, Michael J. McClure, Chen   Huang, Jun Fang, Jinglei Wu, Gary L.Bowlin, Xiumei Mo, Salem S. Al-Deyab,   Mohamed El-Newehy, Electrospinning collagen/chitosan/poly(L-lactic   acid-co-e-caprolactone) to form a vascular graft: mechanical and biological   characterization, Journal of Biomedical Materials Research Part A, accepted   2. Jinglei Wu, Chen Huang, Wei Liu, Anlin Yin, Weiming Chen, Shen Liu, Cunyi   Fan, Xiumei Mo, Gary L. Bowlin, Electrospun nanoyarn scaffold and its   application in tissue engineering, Materials Letter, Materials Letters   2012;89:146-149. 3. Jun Li, Wei Liu, Anlin Yin, Jinglei Wu, Salem S. Al-Deyab   Mohamed El-Newehy, Xiumei Mo Nano-yarns Reinforced Silk Fibroin Composites   Scaffold for Bone Tissue EngineeringJournal of Fibre Bioengineering and   Informatics, 5(1), 1-11, 2012 4. Chun-Yang Wang, Jun-Jian Liu, Cun-Yi Fan,   Xiu-Mei Mo, Hong-Jiang Ruan, Feng-Feng Li, The Effect of Aligned Core-Shell   Nanofibres Delivering NGF on the Promotion of Sciatic Nerve Regeneration,   Journal of Biomaterials Science, Polymer Edition, 23(1-4), 2012 , 167-184 5.   Yan Su, Qianqian Su, Wei Liu, Marcus Lim, Jayarama Reddy Venugopal, Xiumei   Mo, Seeram Ramakrishna, Salem S. Al-Deyab, Mohamed El-Newehy, Controlled   release of bone morphogenetic protein 2 and dexamethasone loaded in   core–shell PLLACL–collagen fibers for use in bone tissue engineering, Acta   Biomaterialia 2012, 8, 763–771 6. Linpeng Fan, Hongsheng Wang, Kuihua Zhang,   Chuanglong He, Zengxiao Cai, Xiumei Mo, Regenerated Silk Fibroin Nanofibrous Matrices   Treated with 75% Ethanol Vapor for Tissue-Engineering Applications Journal of   Biomaterials Science, Polymer Edition, 2012, 23, 497-508 7. 余丕军,王露萍,郭妤,陈炜,莫秀梅, 胶原蛋白-壳聚糖复合纳米纤维膜用于皮肤缺损的修复, 中国组织工程研究与临床康复, 2011, 15(51):9561-9564 8. Chen Huang,   Yanwei Tang, Xin Liu, Alessandra Sutti, Qinfei Ke, Xiumei Mo, Xungai Wang,   Yosry Morsi and Tong Lin. Electrospinning of nanofibres with parallel line   surface texture for improvement of nerve cell growth. Soft Matter, 2011, 7,   10812-7 9. Kuihua Zhang, Anlin Yin, Chen Huang, Chunyang Wang, Xiumei Mo.   Degradation of electrospun SF/P(LLA-CL) blended nanofibrous scaffolds in   vitro. Polymer Degradation and Stability 2011 96: 2266-75 10. A Owida, Rui   Chen, S Patel, Yos Morsi, Xiumei Mo. Artery vessel fabrication using the combined   fused deposition modeling and electrospinning techniques. Rapid Prototyping   Journal. 2011;17:37-44 11. Cuanglong He, Xiaohong Xu, Fan Zhang, Lijun Cao,   Wei Feng, Hongsheng Wang, Xiumei Mo. Fabrication of fibrinogen/P(LLA-CL)   hybrid nanofibrous scaffold for potential soft tissue engineering   applications. Journal of Biomedical Materials Research Part A.   2011;97A:339-47 12. Kuihua Zhang, Q-Z Yu, Xiumei Mo. Fabrication and   Intermolecular Interactions of Silk Fibroin/Hydroxybutyl Chitosan Blended   Nanofibers. International Journal of Molecular Sciences. 2011;12:2187-99 13.   Kuihua Zhang, Yongfang Qian, Hongsheng Wang, Lingpen Fan, Chen Huang, Xiumei   Mo. Electrospun Silk Fibroin-Hydroxybutyl Chitosan Nanofibrous Scaffolds to   Biomimic Extracellular Matrix. Journal of Biomaterials Science-Polymer   Edition. 2011;22:1069-82 14. Fan Zhang, Chuanglong He, Lijun Cao, Feng W,   Wang H, Mo X, et al. Fabrication of gelatin-hyaluronic acid hybrid scaffolds   with tunable porous structures for soft tissue engineering. International   Journal of Biological Macromolecules. 2011;48:474-81 15. Feng Chen, Ying-Jie   Zhu, Kui-Hua Zhang, Jin Wu, Ke-Wei Wang, Qi-Li Tang, Xiumei Mo.   Europium-doped amorphous calcium phosphate porous nanospheres: preparation   and application as luminescent drug carriers, Nanoscale Research Letters   2011, 6:67 16. Yan Su, Xiaoqiang Li, Yinan Liu, Qianqian Su, Marcus Lim,Wei   Qiang and Xiumei Mo, Encapsulation and Controlled Release of Heparin from   Electrospun Poly(L-Lactide-co-ε-Caprolactone) Nanofibers, Journal of Biomaterials   Science-Polymer Edition. 22 (2011) 165–177 17. Chen Huang, Rui Chen, Qinfei   Ke, Yosry Morsic, Kuihua Zhang, Xiumei Mo. Electrospun collagen–chitosan–TPU   nanofibrous scaffolds for tissue engineered tubular grafts, Colloids and   Surfaces B: Biointerfaces 82 (2011) 307–315 18. Yong-Fang Qian, Kui-Hua   Zhang, Feng Chen, Qin-Fei Ke and Xiumei Mo. Cross-Linking of Gelatin and   Chitosan Complex Nanofibers for Tissue-Engineering Scaffolds, Journal of   Biomaterials Science 22 (2011) 1099–1113 19. Chun-Yang Wang, Kui-Hua Zhang,   Cun-Yi Fan, Xiumei Mo, Hong-Jiang Ruan, Feng-Feng Li. Aligned   natural–synthetic polyblend nanofibers for peripheral nerve regeneration,   Acta Biomaterialia 7 (2011) 634–643 20. 余丕军,王露萍,郭妤,陈炜,莫秀梅,蛋白质-多糖复合纳米纤维膜用于皮肤缺损修复实验研究,中国医学工程,201018(4), 1-4. 21. Feng Chen1, Peng Huang,   Xiu-Mei Mo. Electrospinning of Heparin Encapsulated P(LLA-CL) Core/Shell   Nanofibers, Nano Biomedicine And Engineering 2010,2,84-90 22. Zonggang Chen,   Peiwei Wang, B. Wei, Xiumei. Mo, F.Z. Cui. Electrospun collagen–chitosan   nanofiber: A biomimetic extracellular matrix for endothelial cell and smooth   muscle cell. Acta Biomaterialia. 20106372-382. 23. Kuihua Zhang, Yongfang   Qian, Hongsheng Wang, Lingpen Fan, Chen Huang, AnlinYin, Xiumei Mo.   Genipin-crosslinked silk fibroin/hydroxybutyl chitosan nanofibrous scaffolds   for tissue-engineering application. Journal of Biomedical Materials Research   Part A. 2010;95A:870-81 24. Xiaoqiang Li, Yan Su, SP Liu, LJ Tan, Xiumei Mo.   Ramakrishna S. Encapsulation of proteins in poly(L-lactide-co-caprolactone)   fibers by emulsion electrospinning. Colloids and Surfaces B-Biointerfaces.   2010;75:418-24 25. Rui Chen, Qinfei Ke, Xiumei Mo. Preparation and Study of   TPU/Collagen Complex Nanofiber via Electrospinning. Aatcc Review.   2010;10:59-63 26. Xiumei Mo, Hiroo Iwata, Yoshito Ikada. A tissue adhesives   evaluated in vitro and in vivo analysis. Journal of Biomedical Materials   Research Part A. 2010;94A:326-32 27. Zengxiao Cai, Xiumei Mo, Kui-hua Zhang,   Lin-peng Fan, An-lin Yin, Chuang-long He and Hong-sheng Wang, Fabrication of   Chitosan/Silk Fibroin Composite Nanofibers for Wound-dressing Applications,   Int. J. Mol. Sci. 2010, 11, 3529-3539 28. Kuihua Zhang, Hongsheng Wang, Chen   Huang, Yan Su, Xiumei Mo, Yoshito Ikada. Fabrication of silk fibroin blended   P(LLA-CL) nanofibrous scaffolds for tissue engineering. J Biomed Mater Res A.   2010, 93(3): 984-993 29. Kuihua ZHANG, Xiumei Mo, Chen HUANG, Chuanglong HE,   Hongsheng WANG. Electrospun scaffolds from silk fibroin and their cellular   compatibility. J Biomed Mater Res A. 2010, 93(3): 976-983 30. Cai-jiu Gao,   Kui-Hua Zhang, Wei Liu, Xu Zhou, Xiumei Mo. Electrospun Scaffolds from   Gelatin/Hyaluronic Acid and their cellular compatibility. Nonlinear Science   Letters D, 1, 67-72, 2010 31. Kui-Hua Zhang, Hong-Sheng Wang, Cai-Jiu Gao,   Lin-Peng Fan, Xiumei Mo. Fabrication of Electrospinning Silk Fibroin and its   blend nanofibrous Scaffolds for Soft Tissue Engineering. Nonlinear Science   Letters D, 1, 53-58, 2010 32. Rui Chen, Xiaoqiang Li, Qinfei Ke, Chuanglong   He, Xiumei Mo. Fabrication and characterization of collagen (shell)   /thermoplastic polyurethane (core) composite nanofibers by coaxial   electrospinning. e-Polymers, 2010, No009: 1-8 33. Rui Chen, Chen Huang,   Qinfei Ke, Chuanglong He, Hongsheng Wang, Xiumei Mo. Preparation and   Characterization of Coaxial Electrospun Thermoplastic Polyurethane/Collagen   Compound Nanofibers for Tissue Engineering Applications. Colloids and   Surfaces B: Biointerfaces. 2010, 79,315-325 34. Rui Chen, Lijun Qiu, Qinfei   Ke, and Xiumei Mo. Electrospinning Thermoplastic Polyurethane-contained   Collagen Nanofibers for Tissue Engineering Applications. Journal of   Biomaterials science: Polymer Edition, 2009, 20(11): 1513-36 35. R. Chen, Y.   Morsi, A. Owida, X.M Mo and Q.F Ke. Electrospinning of Thermoplastic   Polyurethane Tubular Scaffold For The Construction of Artificial Blood   Vessels. International Journal of Artificial Organ, 2009 July, 32(7): 459 36.   Rui Chen, Qinfei Ke, Xiumei Mo. Preparation and Study of TPU-Collagen Complex   Nanofiber via Electrospinning. AATCC Review, March/April, 2010, 59-66 37. Rui   CHEN, Yosry MORSI, Shital PATEL, Qinfei KE, Xiumei MO Novel Approach via   Combination of Electrospinning and FDM for Tri-leaflet Heart Valve Scaffold   Fabrication. Frontier Materials Science of China. 200934):359-366 38. Yan Su, Xiaoqiang Li,   Hongsheng Wang, Chuanglong He, and Xiumei Mo. Fabrication and   Characterizations of Biodegradable Nanofibrous Mats by Mix and Coaxial   Electrospinning of Poly(L-lactid-co-ε-caprolactone). Journal of Materials   Science: Materials in Medicine. 2009 C, 2009, 20:2285–2294 39. Yan Su,   Xiaoqiang Li , Suiping Liu, Xiumei Mo and Ram Seeram. Controlled Release of   Dual drugs from Emulsion Electrospun Nanofibrous Mats. Colloids and   interfaces B: Biointerfaces, 2009, 73 (2): 376-381 40. Yan Su, Xiaoqiang Li,   Lingjiang Tan Cheng Huang, Xiumei Mo. Electrospun   Poly(L-lactide-co-ε-caprolactone) nanofibers for encapsulating and sustained   releasing proteins. Polymer. 2009, 17 (50): 4212-4219 41. Yongfang Qian,   Xiaoqiang Li, Xiumei Mo. Fabrication and characterization of   Polycaprolactone/Chlorophyllin sodium copper salt nanofibrous mats from   2,2,2-trifluoroethanol solution by electrospinning. Iranian Polymer Journal.   2009, 18(3): 265-274 42. Zonggang Chen, Bo Wei, Xiumei Mo, Fu-zhai Cui. Diameter   Control of Electrospun Chitosan-Collagen Fibers. Polym. Sci Part B: Polym.   Phys. 2009, 47:1949-1955 43. Zonggang Chen, Bo Wei, Xiumei Mo, C.T. Lim, S.   Ramakrishna, Fuzhai Cui. Mechanical properties of electrospun   collagen–chitosan complex single fibers and membrane. Materials Science and   Engineering C. 2009, 29:2428–2435 44. Xiaoqiang Li, Yan Su, Xu Zhou and   Xiumei Mo. Distribution of Sorbitan Monooleate in   poly(l-lactide-co-caprolactone) nanofibers from emulsion electrospinning.   Colloids and Surfaces B: Biointerfaces, 2009, 69: 221-224 45. Huihua Huang,   Chuanglong He, Hongsheng Wang, Xiumei Mo. Preparation of Core-shell   Biodegradable microfibers for long-term Drug delivery. J Biomed Mater Res A.   2009, 90A4:1243–1251 46. Xiaoqiang Li, Yan Su,   Chuanglong He, Hongsheng Wang, and Xiumei Mo. A Study of the Electrospinning   of an H2O–Acetone–PCL Ternary System. Polymers & Polymer Composites,   2009, 17(1) : 37-40 47. Xiaoqiang Li, Yan Su, Rui Chen, Chuanglong He,   Hongsheng Wang, Xiumei Mo. Fabrication and Properties of Core-Shell Structure   P(LLA-CL) Nanofibers by Coaxial Electrospinning. J Appl Polym Sci, 2009,111:   1564–1570 48. Xiaoqiang Li, Yan Su, Chuanglong He, Hongsheng Wang, Fong Hao,   and Xiumei Mo. Sorbitan Monooleate and Poly(L-lactide-co-ε-caprolactone)   Electrospun Nanofibers for Endothelial Cell Interactions. J Biomed Mater Res   A. 2009, Dec 1, 878-885 49. Feng Chen, Yan Su, Xiumei Mo, et al,   Biocompatibility, Alignment Degree and Mechanical Properties of an   Electrospun Chitosan-P(LLA-CL) Fibrous Scaffold, Journal Of Biomaterials   Science-Polymer Edition 20 (14) , 2117-2128, 2009 50. 张鹏云,张建松,徐晓红,莫秀梅,何创龙,生物交联剂京尼平对静电纺明胶纳米纤维膜改性的影响。中国组织工程研究与临床康复. 138),1495992009 51. 张建松,张鹏云,徐晓红,莫秀梅,何创龙,王红声,两种聚(左选乳酸-己内酯)静电纺纳米纤维膜的性能比较。中国组织工程研究与临床康复. 138),1500042009 52. 邱立军 , 王红声 , 何创龙 , 莫秀梅。聚(左旋乳酸-己内酯)/Fe304取向超细纤维的制备及生物相容性。中国组织工程研究与临床康复.1312),22222009


著作:

参编生物医用纺织品,发表文章200多篇。


授权的专利:

申请专利35项,授权8



近几年承担的科研项目:

1. 上海市2005年重大基础研究课题: 编号05DJ14006 “组织工程相关生物材料的基础科学问题研究中的小血管组织工程再建,2005.9-2007.9, 资助金额40, 正在进行。 2. 2005上海市浦江人才计划: 编号05PJ14013 , “生物仿生支架材料用于组织工程” (2005.12-2007.12)。 3. 国家自然科学基金: 编号30570503, “胶原蛋白-甲壳胺复合纳米纤维仿生组织细胞间质及与细胞相互作用的研究”,2006.1-2008.12)。 4. 主持上海市白玉兰科技人才基金,小口径血管组织再生的研究,合同编号:2007B005, 2007.3-2008.3, 资助金额2万。 5. 主持国家高技术研究发展863计划纳米材料与器件专题: 编号2008AA03Z305, “蛋白-多糖复合纳米纤维用于组织修复的研究”2008.4.1-2010.12.31, 资助金额100万。 6. 上海市科委非政府国际合作项目:控释型活性纳米纤维神经导管及心脏瓣膜的研制编号:0852070460030万, 2008.10.1—2010.9.30 7. 上海市科纳米专项:纳米纤维仿生材料用于组织修复的研究,0852nm0340030万,2008.10――2010.9. 8. 国家自然科学基金:编号31070871小口径血管的体内再生研究2011.1-2013.12), 33万。 9. 上海市科纳米专项:蛋白-多糖-PLLA-CL)复合纳米纤维用于小血管组织再生,编号:11nm0506200,(2011.12-2014.09 10. 国家自然科学基金:编号31271035 “双营养因子缓释型轴向取向纳米纤维神经导管诱导长距离神经再生的研究2013.1-2016.12



国际交流与合作:

与美国,新加坡,澳大利亚等国家有合作: Viginia Commenwealth University,   National University of Singapore, Deakin University, Swinburne University of   Technology



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Emailxmm@dhu.edu.cn

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