学术报告
发布人: 星禧   发布时间: 2019-12-25    浏览次数:

主讲人简介:

Dr. Chun Xu, 正高级 NHMRC Senior Research Officer, NHMRC Early Career Fellow, School of Dentistry, The University of Queensland. Dr. Chun Xu received his Ph.D. in Biomedical Engineering and Nanotechnology at The University of Queensland, Australia in 2016. He is currently a NHMRC Senior Research Officer and C.J. Martin fellow at The University of Queensland. He has published over 43 peer-reviewed scientific papers in top journals including Adv. Mater., Chem. Mater., Small and hold 4 patents. In the last 3 years he has attracted 10 competitive grants including 1 prestigious NHMRC Fellow. He is a regular reviewer for several scientific journals and for NHMRC, ARC grants. He also serves as review editor on the editorial board of Nanoscience, Frontiers in Chemistry. He has received several awards such as WOS Young Science Ambassador Award, Frontiers Rising Star Award. He is a member of ISO experts committee for Nanoscience and Nanotechnologies.


报告摘要:

Nanoparticles possess unique physical, chemical and biological properties due to the nanosized effects and offer various advantages for biomedical applications such as drug delivery and tissue engineering. Mesoporous silica nanoparticles (MSNs) are of special interested due to their good biocompatibility, high stability, rigid framework, well-defined pore structure, easily controllable morphology and tunable surface chemistry. MSNs based delivery system offer a promising strategy to improve the drawbacks of traditional therapeutic drugs such as low stability and difficulty to cross the cell membranes. Recently, the development of MSNs with large pores enable the loading and delivery of large therapeutic molecules including proteins and genes. In particular, enhanced stability, improved activity, responsive release and intracellular delivery of proteins/genes are achieved with novel MSNs.